Alanine Aminotransferase and Bilirubin Dynamic Evolution Pattern as a Novel Model for the Prediction of Acute Liver Failure in Drug-Induced Liver Injury

• Main Authors: Ruiyuan Yang (Author), Kexin Li (Author), Cailun Zou (Author), Aileen Wee (Author), Jimin Liu (Author), Liwei Liu (Author), Min Li (Author), Ting Wu (Author), Yu Wang (Author), Zikun Ma (Author), Yan Wang (Author), Jingyi Liu (Author), Ang Huang (Author), Ying Sun (Author), Binxia Chang (Author), Qingsheng Liang (Author), Jidong Jia (Author), Zhengsheng Zou (Author), Xinyan Zhao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aims: To develop, optimize, and validate a novel model using alanine aminotransferase (ALT) and total bilirubin (TB) dynamic evolution patterns in predicting acute liver failure (ALF) in drug-induced liver injury (DILI) patients.Methods: The demographics, clinical data, liver biopsy, and outcomes of...