In Vivo Evaluation of the Acute Pulmonary Response to Poractant Alfa and Bovactant Treatments in Lung-Lavaged Adult Rabbits and in Preterm Lambs with Respiratory Distress Syndrome

• Main Authors: Francesca Ricci (Author), Fabrizio Salomone (Author), Elke Kuypers (Author), Daan Ophelders (Author), Maria Nikiforou (Author), Monique Willems (Author), Tobias Krieger (Author), Xabier Murgia (Author), Matthias Hütten (Author), Boris W. Kramer (Author), Federico Bianco (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundPoractant alfa (Curosurf®) and Bovactant (Alveofact®) are two animal-derived pulmonary surfactants preparations approved for the treatment of neonatal respiratory distress syndrome (nRDS). They differ in their source, composition, pharmaceutical form, and clinical dose. How much these diff...