Rho-Kinase 1/2 Inhibition Prevents Transforming Growth Factor-β-Induced Effects on Pulmonary Remodeling and Repair

Rho-Kinase 1/2 Inhibition Prevents Transforming Growth Factor-β-Induced Effects on Pulmonary Remodeling and Repair

Transforming growth factor (TGF)-β-induced myofibroblast transformation and alterations in mesenchymal-epithelial interactions contribute to chronic lung diseases such as chronic obstructive pulmonary disease (COPD), asthma and pulmonary fibrosis. Rho-associated coiled-coil-forming protein kinase (R...

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Main Authors: Xinhui Wu (Author), Vicky Verschut (Author), Manon E. Woest (Author), John-P (Author), Ana Matias (Author), Gino Villetti (Author), Alessandro Accetta (Author), Fabrizio Facchinetti (Author), Reinoud Gosens (Author), Loes E. M. Kistemaker (Author)
Format: Book
Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
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