Chain-Branched Polyhydroxylated Octahydro-<i>1H</i>-Indoles as Potential Leads against Lysosomal Storage Diseases

• Main Authors: Juan C. Estévez (Author), Marcos A. González (Author), M. Carmen Villaverde (Author), Yuki Hirokami (Author), Atsushi Kato (Author), Fredy Sussman (Author), David Reza (Author), Ramón J. Estévez (Author)
• Format: Book
• Published: MDPI AG, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Here, the synthesis and glycosidase inhibition properties of the two first known 3-ethyloctahydro-1<i>H</i>-indole-4,5,6-triols are reported. This study shows the transformation of <span style="font-variant: small-caps;">d</span>-glucose into polyhydroxylated 1-(2-n...