Design, Synthesis, and Antitumor Evaluation of an Opioid Growth Factor Bioconjugate Targeting Pancreatic Ductal Adenocarcinoma

• Hoofdauteurs: Justyna Budka (Auteur), Dawid Debowski (Auteur), Shaoshan Mai (Auteur), Magdalena Narajczyk (Auteur), Stanislaw Hac (Auteur), Krzysztof Rolka (Auteur), Eirinaios I. Vrettos (Auteur), Andreas G. Tzakos (Auteur), Iwona Inkielewicz-Stepniak (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2024-02-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Pancreatic ductal adenocarcinoma (PDAC) presents a formidable challenge with high lethality and limited effective drug treatments. Its heightened metastatic potential further complicates the prognosis. Owing to the significant toxicity of current chemotherapeutics, compounds like [Met<sup>5<...