Does CD4+CD25+foxp3+ cell (Treg) and IL-10 profile determine susceptibility to immune reconstitution inflammatory syndrome (IRIS) in HIV disease?

• Main Authors: Saravanan Shanmugam (Author), Lloyd Charmaine AC (Author), Balakrishnan Pachamuthu (Author), Sekar Ramalingam (Author), Murugavel Kailapuri G (Author), Velu Vijayakumar (Author), Vignesh Ramachandran (Author), Shankar Esaki (Author), Solomon Suniti (Author), Kumarasamy Nagalingeswaran (Author)
• Format: Book
• Published: BMC, 2008-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>HIV-specific T-lymphocyte responses that underlie IRIS are incomplete and largely remain hypothetical. Of the several mechanisms presented by the host to control host immunological damage, Treg cells are believed to play a critical role. Using the available exper...