Post‐operative mortality and recurrence patterns in pancreatic cancer according to KRAS mutation and CDKN2A, p53, and SMAD4 expression

• Main Authors: Yohei Masugi (Author), Manabu Takamatsu (Author), Mariko Tanaka (Author), Kensuke Hara (Author), Yosuke Inoue (Author), Tsuyoshi Hamada (Author), Tatsunori Suzuki (Author), Junichi Arita (Author), Yuki Hirose (Author), Yoshikuni Kawaguchi (Author), Yousuke Nakai (Author), Atsushi Oba (Author), Naoki Sasahira (Author), Gaku Shimane (Author), Tsuyoshi Takeda (Author), Keisuke Tateishi (Author), Sho Uemura (Author), Mitsuhiro Fujishiro (Author), Kiyoshi Hasegawa (Author), Minoru Kitago (Author), Yu Takahashi (Author), Tetsuo Ushiku (Author), Kengo Takeuchi (Author), Michiie Sakamoto (Author), for the GTK Pancreatic Cancer Study Group in Japan (Author)
• Format: Book
• Published: Wiley, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Alterations in KRAS, CDKN2A (p16), TP53, and SMAD4 genes have been major drivers of pancreatic carcinogenesis. The clinical course of patients with pancreatic cancer in relation to these driver alterations has not been fully characterised in large populations. We hypothesised that pancreati...