Zebrafish as a model to assess cancer heterogeneity, progression and relapse

• मुख्य लेखकों: Jessica S. Blackburn (लेखक), David M. Langenau (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: The Company of Biologists, 2014-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Clonal evolution is the process by which genetic and epigenetic diversity is created within malignant tumor cells. This process culminates in a heterogeneous tumor, consisting of multiple subpopulations of cancer cells that often do not contain the same underlying mutations. Continuous selective pre...