Molecular, immunological, and biological characterization of Tityus serrulatus venom hyaluronidase: new insights into its role in envenomation.

• Main Authors: Carolina Campolina Rebello Horta (Author), Bárbara de Freitas Magalhães (Author), Bárbara Bruna Ribeiro Oliveira-Mendes (Author), Anderson Oliveira do Carmo (Author), Clara Guerra Duarte (Author), Liza Figueiredo Felicori (Author), Ricardo Andrez Machado- (Author), Carlos Chávez-Olórtegui (Author), Evanguedes Kalapothakis (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Scorpionism is a public health problem in Brazil, and Tityus serrulatus (Ts) is primarily responsible for severe accidents. The main toxic components of Ts venom are low-molecular-weight neurotoxins; however, the venom also contains poorly characterized high-molecular-weight enzymes. Hya...