Preparation of a Sunitinib loaded microemulsion for ocular delivery and evaluation for the treatment of corneal neovascularization in vitro and in vivo

• Main Authors: Jieran Shi (Author), Jingjing Yang (Author), Haohang Xu (Author), Qing Luo (Author), Jun Sun (Author), Yali Zhang (Author), Zhen Liang (Author), Ningmin Zhao (Author), Junjie Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Corneal neovascularization (CNV) is a pathological condition that can disrupt corneal transparency, thus harming visual acuity. However, there is no effective drug to treat CNV. Sunitinib (STB), a small-molecule multiple receptor tyrosine kinase inhibitor, was shown to have an effect on...