Beautiful small: Misleading large randomized controlled trials? The example of colloids for volume resuscitation
In anesthesia and intensive care, treatment benefits that were claimed on the basis of small or modest-sized trials have repeatedly failed to be confirmed in large randomized controlled trials. A well-designed small trial in a homogeneous patient population with high event rates could yield conclusi...
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Wolters Kluwer Medknow Publications,
2015-01-01T00:00:00Z.
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