Monitoring glycation levels of a bispecific monoclonal antibody at subunit level by ultrahigh-resolution MALDI FT-ICR mass spectrometry

• Main Authors: Christoph Gstöttner (Author), Dietmar Reusch (Author), Markus Haberger (Author), Irina Dragan (Author), Peter Van Veelen (Author), David P. A. Kilgour (Author), Yury O. Tsybin (Author), Yuri E. M. van der Burgt (Author), Manfred Wuhrer (Author), Simone Nicolardi (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bispecific monoclonal antibodies (BsAbs) are engineered proteins with multiple functionalities and properties. The "bi-specificity" of these complex biopharmaceuticals is a key characteristic for the development of novel and more effective therapeutic strategies. The high structural comple...