Phosphorylation and Dephosphorylation of Tau Protein During Synthetic Torpor

• Главные авторы: Marco Luppi (Автор), Timna Hitrec (Автор), Alessia Di Cristoforo (Автор), Fabio Squarcio (Автор), Agnese Stanzani (Автор), Alessandra Occhinegro (Автор), Pierfrancesco Chiavetta (Автор), Domenico Tupone (Автор), Giovanni Zamboni (Автор), Roberto Amici (Автор), Matteo Cerri (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2019-06-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Tau protein is of primary importance for many physiological processes in neurons, where it affects the dynamics of the microtubule system. When hyperphosphorylated (PP-Tau), Tau monomers detach from microtubules and tend to aggregate firstly in oligomers, and then in neurofibrillary tangles, as it o...