Proarrhythmia risk prediction using human induced pluripotent stem cell-derived cardiomyocytes

• Main Authors: Daiju Yamazaki (Author), Takashi Kitaguchi (Author), Masakazu Ishimura (Author), Tomohiko Taniguchi (Author), Atsuhiro Yamanishi (Author), Daisuke Saji (Author), Etsushi Takahashi (Author), Masao Oguchi (Author), Yuta Moriyama (Author), Sanae Maeda (Author), Kaori Miyamoto (Author), Kaoru Morimura (Author), Hiroki Ohnaka (Author), Hiroyuki Tashibu (Author), Yuko Sekino (Author), Norimasa Miyamoto (Author), Yasunari Kanda (Author)
• Format: Book
• Published: Elsevier, 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are expected to become a useful tool for proarrhythmia risk prediction in the non-clinical drug development phase. Several features including electrophysiological properties, ion channel expression profile and drug responses were...