Impact of mucus modulation by N-acetylcysteine on nanoparticle toxicity

• Main Authors: Enkeleda Meziu (Author), Kristela Shehu (Author), Marcus Koch (Author), Marc Schneider (Author), Annette Kraegeloh (Author)
• Formato: Livro
• Publicado em: Elsevier, 2023-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Human respiratory mucus is a biological hydrogel that forms a protective barrier for the underlying epithelium. Modulation of the mucus layer has been employed as a strategy to enhance transmucosal drug carrier transport. However, a drawback of this strategy is a potential reduction of the mucus bar...