Survival motor neuron deficiency slows myoblast fusion through reduced myomaker and myomixer expression

• Main Authors: Nikki M. McCormack (Author), Eric Villalón (Author), Coralie Viollet (Author), Anthony R. Soltis (Author), Clifton L. Dalgard (Author), Christian L. Lorson (Author), Barrington G. Burnett (Author)
• Formato: Livro
• Publicado em: Wiley, 2021-08-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Spinal muscular atrophy is an inherited neurodegenerative disease caused by insufficient levels of the survival motor neuron (SMN) protein. Recently approved treatments aimed at increasing SMN protein levels have dramatically improved patient survival and have altered the disease...