Molecular Mechanisms and Therapeutic Strategies of Chronic Renal Injury: The Role of Nuclear Factor κB Activation in the Development of Renal Fibrosis

• Main Authors: Satoshi Tamada (Author), Toshihiro Asai (Author), Nobuyuki Kuwabara (Author), Tomoaki Iwai (Author), Junji Uchida (Author), Kae Teramoto (Author), Noriko Kaneda (Author), Tokihito Yukimura (Author), Toshiyuki Komiya (Author), Tatsuya Nakatani (Author), Katsuyuki Miura (Author)
• Format: Book
• Published: Elsevier, 2006-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: Tubulointerstitial fibrosis is a common feature of many progressive renal diseases and is a main determinant that leads to an irreversible loss of renal function. In chronic cyclosporin A nephrotoxicity, we previously reported that inflammatory responses such as macrophage infiltration pr...