Mosquito cell-derived West Nile virus replicon particles mimic arbovirus inoculum and have reduced spread in mice.

• Hoofdauteurs: Brendan T Boylan (Auteur), Fernando R Moreira (Auteur), Tim W Carlson (Auteur), Kristen A Bernard (Auteur)
• Formaat: Boek
• Gepubliceerd in: Public Library of Science (PLoS), 2017-02-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Half of the human population is at risk of infection by an arthropod-borne virus. Many of these arboviruses, such as West Nile, dengue, and Zika viruses, infect humans by way of a bite from an infected mosquito. This infectious inoculum is insect cell-derived giving the virus particles distinct qual...