FTO protects human granulosa cells from chemotherapy-induced cytotoxicity

• Main Authors: Rongli Wang (Author), Wei Wang (Author), Lijun Wang (Author), Linnan Yuan (Author), Feiyan Cheng (Author), Xin Guan (Author), Nini Zheng (Author), Xinyuan Yang (Author)
• Format: Book
• Published: BMC, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Premature ovarian failure (POF) is a serious problem for young women who receive chemotherapy, and its pathophysiological basis is the dysfunction of granulosa cells. According to previous reports, menstrual-derived stem cells (MenSCs) can restore ovarian function and folliculoge...