Sepsis induces interleukin 6, gp130/JAK2/STAT3, and muscle wasting

• मुख्य लेखकों: Lukas Zanders (लेखक), Melanie Kny (लेखक), Alexander Hahn (लेखक), Sibylle Schmidt (लेखक), Sebastian Wundersitz (लेखक), Mihail Todiras (लेखक), Ines Lahmann (लेखक), Arnab Bandyopadhyay (लेखक), Tobias Wollersheim (लेखक), Lars Kaderali (लेखक), Friedrich C. Luft (लेखक), Carmen Birchmeier (लेखक), Steffen Weber‐Carstens (लेखक), Jens Fielitz (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2022-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Sepsis and inflammation can cause intensive care unit‐acquired weakness (ICUAW). Increased interleukin‐6 (IL‐6) plasma levels are a risk factor for ICUAW. IL‐6 signalling involves the glycoprotein 130 (gp130) receptor and the JAK/STAT‐pathway, but its role in sepsis‐induced muscl...