Development and Evaluation of a Reconstitutable Dry Suspension to Improve the Dissolution and Oral Absorption of Poorly Water-Soluble Celecoxib

• Автори: Hye-In Kim (Автор), Sang Yeob Park (Автор), Seok Ju Park (Автор), Jewon Lee (Автор), Kwan Hyung Cho (Автор), Jun-Pil Jee (Автор), Hee-Cheol Kim (Автор), Han-Joo Maeng (Автор), Dong-Jin Jang (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2018-08-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

This study aims at developing and evaluating reconstitutable dry suspension (RDS) improved for dissolution rate, oral absorption, and convenience of use of poorly water-soluble celecoxib (CXB). Micro-sized CXB particle was used to manufacture nanosuspension by using bead milling and then RDS was mad...