A real-world study of treatment patterns following disease progression in epithelial ovarian cancer patients undergoing poly-ADP-ribose polymerase inhibitor maintenance therapy

• Главные авторы: Nan Zhang (Автор), Hong Zheng (Автор), Yunong Gao (Автор), Tong Shu (Автор), Hongguo Wang (Автор), Yan Cai (Автор)
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• Опубликовано: BMC, 2024-03-01T00:00:00Z.
• Предметы: article
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Abstract Background The efficacy of subsequent therapy after poly-ADP-ribose polymerase (PARP) inhibitor maintenance treatment has raised concerns. Retrospective studies show worse outcomes for platinum-based chemotherapy after progression of PARP inhibitor-maintenance therapy, especially in BRCA-mu...