Therapeutic Potential of the Cyclin-Dependent Kinase Inhibitor Flavopiridol on c-Myc Overexpressing Esophageal Cancer

Therapeutic Potential of the Cyclin-Dependent Kinase Inhibitor Flavopiridol on c-Myc Overexpressing Esophageal Cancer

Tumors with elevated c-Myc expression often exhibit a highly aggressive phenotype, and c-Myc amplification has been shown to be frequent in esophageal cancer. Emerging data suggests that synthetic lethal interactions between c-Myc pathway activation and small molecules inhibition involved in cell cy...

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Main Authors: Md Sazzad Hassan (Author), Nicholas Cwidak (Author), Chloe Johnson (Author), Silvio Däster (Author), Serenella Eppenberger-Castori (Author), Niranjan Awasthi (Author), Jun Li (Author), Margaret A. Schwarz (Author), Urs von Holzen (Author)
Format: Book
Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
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3rd Floor Main Library

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