Sex Differences in the Pro-Angiogenic Response of Human Endothelial Cells: Focus on PFKFB3 and FAK Activation

• Main Authors: Carlotta Boscaro (Author), Annalisa Trenti (Author), Chiara Baggio (Author), Chiara Scapin (Author), Lucia Trevisi (Author), Andrea Cignarella (Author), Chiara Bolego (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Female hormones and sex-specific factors are established determinants of endothelial function, yet their relative contribution to human endothelium phenotypes has not been defined. Using human umbilical vein endothelial cells (HUVECs) genotyped by donor's sex, we investigated the influence of s...