Curcumin's Metabolites, Tetrahydrocurcumin and Octahydrocurcumin, Possess Superior Anti-inflammatory Effects in vivo Through Suppression of TAK1-NF-κB Pathway

• Main Authors: Zhen-Biao Zhang (Author), Dan-Dan Luo (Author), Jian-Hui Xie (Author), Yan-Fang Xian (Author), Zheng-Quan Lai (Author), Yu-Hong Liu (Author), Wei-Hai Liu (Author), Jian-Nan Chen (Author), Xiao-Ping Lai (Author), Zhi-Xiu Lin (Author), Zi-Ren Su (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Curcumin (CUR), a promising naturally occurring dietary compound, is commonly recognized as the potential anti-inflammatory agent. While the application of CUR was hampered by its low stability and poor systemic bioavailability, it has been suggested that the biological activities of CUR are intimat...