Activation of the Alpha 7 Nicotinic Acetylcholine Receptor by GTS-21 Mitigates Contrast Nephropathy in a Rat Model

Activation of the Alpha 7 Nicotinic Acetylcholine Receptor by GTS-21 Mitigates Contrast Nephropathy in a Rat Model

Introduction: Contrast nephropathy (CN) is characterized by oxidative stress, vasoconstriction, tubular toxicity, and hypoxia of the renal medulla. We aimed to test the therapeutic effects of an α7 nicotinic acetylcholine receptor (nAChR) agonist, GTS-21, in an experimental CN model. Methods: Male S...

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Main Authors: Seckin Akcay (Author), Zarife Nigar Ozdemir Kumral (Author), Ozlem Tugce Cilingir-Kaya (Author), Irem Peker Eyüboglu (Author), Mustafa Akkiprik (Author), Berrak C. Yegen (Author), Mehmet Koc (Author)
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Published: Karger Publishers, 2024-07-01T00:00:00Z.
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