Interleukin-27 decreases ghrelin production through signal transducer and activator of transcription 3-mechanistic target of rapamycin signaling

• Main Authors: Heng Zhang (Author), Qingjie Li (Author), Yuxin Teng (Author), Yubi Lin (Author), Shaojian Li (Author), Tingfeng Qin (Author), Linxi Chen (Author), Jiana Huang (Author), Hening Zhai (Author), Quan Yu (Author), Geyang Xu (Author)
• Format: Book
• Published: Elsevier, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Interleukin-27 (IL-27), a heterodimeric cytokine, plays a protective role in diabetes. Ghrelin, a gastric hormone, provides a hunger signal to the central nervous system to stimulate food intake. The relationship between IL-27 and ghrelin is still unexplored. Here we investigated that signal transdu...