IKKβ mediates homeostatic function in inflammation via competitively phosphorylating AMPK and IκBα

• Main Authors: Juan Liu (Author), Yuxin Zhuang (Author), Jianlin Wu (Author), Qiang Wu (Author), Meixian Liu (Author), Yue Zhao (Author), Zhongqiu Liu (Author), Caiyan Wang (Author), Linlin Lu (Author), Yingjiao Meng (Author), Kawai Lei (Author), Xiaojuan Li (Author), Qibiao Wu (Author), Elaine Lai-Han Leung (Author), Zhengyang Guo (Author), Liang Liu (Author), Ting Li (Author)
• Format: Book
• Published: Elsevier, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inhibitor of nuclear factor kappa-B kinase subunit beta (IKKβ) is one of important kinases in inflammation to phosphorylate inhibitor of nuclear factor kappa-B (IκBα) and then activate nuclear factor kappa-B (NF-κB). Inhibition of IKKβ has been a therapeutic strategy for inflammatory and autoimmune...