Enhanced Antitumor Activity by the Combination of Dasatinib and Selinexor in Chronic Myeloid Leukemia

• Main Authors: Mariarita Spampinato (Author), Tatiana Zuppelli (Author), Ilaria Dulcamare (Author), Lucia Longhitano (Author), Domenico Sambataro (Author), Annalisa Santisi (Author), Amer M. Alanazi (Author), Ignazio A. Barbagallo (Author), Nunzio Vicario (Author), Rosalba Parenti (Author), Alessandra Romano (Author), Giuseppe Musumeci (Author), Giovanni Li Volti (Author), Giuseppe A. Palumbo (Author), Francesco Di Raimondo (Author), Anna Nicolosi (Author), Sebastiano Giallongo (Author), Vittorio Del Fabro (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Chronic myeloid leukemia is a hematological malignancy characterized by the abnormal proliferation of leukemic cells. Despite significant progress with tyrosine kinase inhibitors, such as Dasatinib, resistance remains a challenge. The aim of the present study was to investigate the poten...