Model‐Based Analysis Reveals a Sustained and Dose‐Dependent Acceleration of Wound Healing by VEGF‐A mRNA (AZD8601)

Model‐Based Analysis Reveals a Sustained and Dose‐Dependent Acceleration of Wound Healing by VEGF‐A mRNA (AZD8601)

Intradermal delivery of AZD8601, an mRNA designed to produce vascular endothelial growth factor A (VEGF‐A), has previously been shown to accelerate cutaneous wound healing in a murine diabetic model. Here, we develop population pharmacokinetic and pharmacodynamic models aiming to quantify the effect...

Full description

Saved in:
Bibliographic Details
Main Authors: Joachim Almquist (Author), S. Michaela Rikard (Author), Maria Wågberg (Author), Anthony C. Bruce (Author), Peter Gennemark (Author), Regina Fritsche‐Danielson (Author), Kenneth R. Chien (Author), Shayn M. Peirce (Author), Kenny Hansson (Author), Anna Lundahl (Author)
Format: Book
Published: Wiley, 2020-07-01T00:00:00Z.
Subjects:
article
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available

Similar Items