Acid-switchable nanoparticles induce self-adaptive aggregation for enhancing antitumor immunity of natural killer cells

• Main Authors: Xiangshi Sun (Author), Xiaoxuan Xu (Author), Jue Wang (Author), Xinyue Zhang (Author), Zitong Zhao (Author), Xiaochen Liu (Author), Guanru Wang (Author), Lesheng Teng (Author), Xia Chen (Author), Dangge Wang (Author), Yaping Li (Author)
• Format: Book
• Published: Elsevier, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Deficiency of natural killer (NK) cells shows a significant impact on tumor progression and failure of immunotherapy. It is highly desirable to boost NK cell immunity by upregulating active receptors and relieving the immunosuppressive tumor microenvironment. Unfortunately, mobilization of NK cells...