Kaempferol-Mediated Sensitization Enhances Chemotherapeutic Efficacy of Sorafenib Against Hepatocellular Carcinoma: An In Silico and In Vitro Approach

• मुख्य लेखकों: Bhagyalakshmi Nair (लेखक), Ruby John Anto (लेखक), Sabitha M (लेखक), Lekshmi R. Nath (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Tabriz University of Medical Sciences, 2020-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Purpose: Sorafenib is the sole FDA approved drug conventionally used for the treatment of advanced hepatocellular carcinoma (HCC). Despite of the beneficial use of sorafenib in the treatment of HCC, multidrug resistance still remains a challenge. HCC is inherently known as chemotherapy resistant tum...