Kaempferol-Mediated Sensitization Enhances Chemotherapeutic Efficacy of Sorafenib Against Hepatocellular Carcinoma: An In Silico and In Vitro Approach

• Main Authors: Bhagyalakshmi Nair (Author), Ruby John Anto (Author), Sabitha M (Author), Lekshmi R. Nath (Author)
• Formato: Livro
• Publicado em: Tabriz University of Medical Sciences, 2020-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Purpose: Sorafenib is the sole FDA approved drug conventionally used for the treatment of advanced hepatocellular carcinoma (HCC). Despite of the beneficial use of sorafenib in the treatment of HCC, multidrug resistance still remains a challenge. HCC is inherently known as chemotherapy resistant tum...