miR-125a Promotes the Progression of Giant Cell Tumors of Bone by Stimulating IL-17A and β-Catenin Expression

miR-125a Promotes the Progression of Giant Cell Tumors of Bone by Stimulating IL-17A and β-Catenin Expression

Giant cell tumors of bone (GCTBs) exhibit high recurrence and aggressive bone lytic behavior; but, the mechanism of GCTB progression is largely unknown. In GCTB, we detected abundant levels of miR-125a, which were associated with tumor extension, grade, and recurrence. miR-125a stimulates stromal ce...

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Main Authors: Hua Jin (Author), Dian-Wei Li (Author), Shu-Nan Wang (Author), Song Luo (Author), Qing Li (Author), Ping Huang (Author), Jian-Min Wang (Author), Meng Xu (Author), Cheng-Xiong Xu (Author)
Format: Book
Published: Elsevier, 2018-12-01T00:00:00Z.
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