Prediction of Liver Weight Recovery by an Integrated Metabolomics and Machine Learning Approach After 2/3 Partial Hepatectomy

• Main Authors: Runbin Sun (Author), Haokai Zhao (Author), Shuzhen Huang (Author), Ran Zhang (Author), Zhenyao Lu (Author), Sijia Li (Author), Guangji Wang (Author), Jiye Aa (Author), Yuan Xie (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Liver has an ability to regenerate itself in mammals, whereas the mechanism has not been fully explained. Here we used a GC/MS-based metabolomic method to profile the dynamic endogenous metabolic change in the serum of C57BL/6J mice at different times after 2/3 partial hepatectomy (PHx), and nine ma...