Rapid emergence of multidrug resistant, H58-lineage Salmonella typhi in Blantyre, Malawi.

• Main Authors: Nicholas A Feasey (Author), Katherine Gaskell (Author), Vanessa Wong (Author), Chisomo Msefula (Author), George Selemani (Author), Save Kumwenda (Author), Theresa J Allain (Author), Jane Mallewa (Author), Neil Kennedy (Author), Aisleen Bennett (Author), Joram O Nyirongo (Author), Patience A Nyondo (Author), Madalitso D Zulu (Author), Julian Parkhill (Author), Gordon Dougan (Author), Melita A Gordon (Author), Robert S Heyderman (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Between 1998 and 2010, S. Typhi was an uncommon cause of bloodstream infection (BSI) in Blantyre, Malawi and it was usually susceptible to first-line antimicrobial therapy. In 2011 an increase in a multidrug resistant (MDR) strain was detected through routine bacteriological surveillance conducted a...