Pentabromopseudilin: a myosin V inhibitor suppresses TGF-β activity by recruiting the type II TGF-β receptor to lysosomal degradation

• Główni autorzy: Wang Shih-Wei (Autor), Chung Chih-Ling (Autor), Yu-Chen Kao (Autor), René Martin (Autor), Hans-Joachim Knölker (Autor), Meng-Shin Shiao (Autor), Chun-Lin Chen (Autor)
• Format: Książka
• Wydane: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Pentabromopseudilin (PBrP) is a marine antibiotic isolated from the marine bacteria Pseudomonas bromoutilis and Alteromonas luteoviolaceus. PBrP exhibits antimicrobial, anti-tumour, and phytotoxic activities. In mammalian cells, PBrP is known to act as a reversible and allosteric inhibitor of myosin...