The Inhibitory T Cell Receptors PD1 and 2B4 Are Differentially Regulated on CD4 and CD8 T Cells in a Mouse Model of Non-alcoholic Steatohepatitis

• Main Authors: Cordula Hansel (Author), Stephanie Erschfeld (Author), Maike Baues (Author), Twan Lammers (Author), Ralf Weiskirchen (Author), Christian Trautwein (Author), Daniela C. Kroy (Author), Hannah K. Drescher (Author)
• 格式: 图书
• 出版: Frontiers Media S.A., 2019-03-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Infiltrating CD4 and CD8 T cells have been shown to worsen inflammatory liver damage in non-alcoholic steatohepatitis (NASH). Inhibitory T cell receptors such as the programmed cell death protein 1 (PD1) and the natural killer cell receptor 2B4 regulate the activity of CD4 and CD8 T cells and theref...