Network pharmacology modeling identifies synergistic interaction of therapeutic and toxicological mechanisms for Tripterygium hypoglaucum Hutch

• Main Authors: Dan Zhang (Author), Yizhu Dong (Author), Jintao Lv (Author), Bing Zhang (Author), Xiaomeng Zhang (Author), Zhijian Lin (Author)
• פורמט: ספר
• יצא לאור: BMC, 2021-01-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Abstract Background Tripterygium hypoglaucum Hutch (THH) both has prominent efficacy and unwarranted toxicity in the treatment of autoimmune diseases. Nevertheless, its pharmacological and toxicological profiles still remain to be elucidated. In the current study, the network pharmacology approach w...