Network pharmacology modeling identifies synergistic interaction of therapeutic and toxicological mechanisms for Tripterygium hypoglaucum Hutch

• Главные авторы: Dan Zhang (Автор), Yizhu Dong (Автор), Jintao Lv (Автор), Bing Zhang (Автор), Xiaomeng Zhang (Автор), Zhijian Lin (Автор)
• Формат: ‌
• Опубликовано: BMC, 2021-01-01T00:00:00Z.
• Предметы: article
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Abstract Background Tripterygium hypoglaucum Hutch (THH) both has prominent efficacy and unwarranted toxicity in the treatment of autoimmune diseases. Nevertheless, its pharmacological and toxicological profiles still remain to be elucidated. In the current study, the network pharmacology approach w...