Bidirectional Regulation of Human Colonic Smooth Muscle Contractility by Tachykinin NK2 Receptors

• Main Authors: Akihiro Nakamura (Author), Takahiro Tanaka (Author), Akio Imanishi (Author), Makiko Kawamoto (Author), Masao Toyoda (Author), Gaku Mizojiri (Author), Yasuhiro Tsukimi (Author)
• Format: Book
• Published: Elsevier, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: In this study, we attempted to clarify the mechanism of tachykinin-induced motor response in isolated smooth muscle preparations of the human colon. Fresh specimens of normal colon were obtained from patients suffering from colonic cancer. Using mucosa-free smooth muscle strips, smooth mu...