Safety of intravenously applied mistletoe extract - results from a phase I dose escalation study in patients with advanced cancer

• Main Authors: Roman Huber (Author), Dietrich Schlodder (Author), Carola Effertz (Author), Sabine Rieger (Author), Wilfried Tröger (Author)
• Format: Book
• Published: BMC, 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Mistletoe extracts have anti-tumor properties and are approved for subcutaneous use in cancer patients. Data on Intravenous application are limited. Methods An aqueous extract from pine-mistletoe was used to investigate maximum tolerable dose (MTD) and safety of intravenous appli...