Tyrosine phosphatase SHP2 inhibitors in tumor-targeted therapies

• Váldodahkkit: Zhendong Song (Dahkki), Meijing Wang (Dahkki), Yang Ge (Dahkki), Xue-Ping Chen (Dahkki), Ziyang Xu (Dahkki), Yang Sun (Dahkki), Xiao-Feng Xiong (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2021-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Src homology containing protein tyrosine phosphatase 2 (SHP2) represents a noteworthy target for various diseases, serving as a well-known oncogenic phosphatase in cancers. As a result of the low cell permeability and poor bioavailability, the traditional inhibitors targeting the protein tyrosine ph...