The effects of pH, surfactant, ion concentration, coformer, and molecular arrangement on the solubility behavior of myricetin cocrystals

• Main Authors: Shuzhen Ren (Author), Mingyu Liu (Author), Chao Hong (Author), Guowen Li (Author), Jiabin Sun (Author), Jianying Wang (Author), Lei Zhang (Author), Yan Xie (Author)
• Format: Book
• Published: Elsevier, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pharmaceutical cocrystals are a promising technology that can be used to improve the solubility of poor aqueous compounds. The objective of this study was to systematically investigate the solubility of myricetin (MYR) cocrystals, including their kinetic solubility, thermodynamic solubility, and int...