Transcriptional Suppression of miR-7 by MTA2 Induces Sp1-Mediated KLK10 Expression and Metastasis of Cervical Cancer

• Main Authors: Chia-Liang Lin (Author), Tsung-Ho Ying (Author), Shun-Fa Yang (Author), Shih-Wei Wang (Author), Shih-Ping Cheng (Author), Jie-Jen Lee (Author), Yi-Hsien Hsieh (Author)
• Format: Book
• Published: Elsevier, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

MTA2 is involved in tumor proliferation and metastasis. However, the role of MTA2 in cervical cancer thus far has not been identified. In this study, we report that elevated expression of MTA2 negatively correlates with Kallikrein-10 (KLK10) expression and poor prognosis of cervical cancer patients....