Leptin Promoted IL-17 Production from ILC2s in Allergic Rhinitis

• Autori principali: Yanhui Wen (Autore), Qingxiang Zeng (Autore), Xi Luo (Autore), Renqiang Ma (Autore), Yiquan Tang (Autore), Wenlong Liu (Autore)
• Natura: Libro
• Pubblicazione: Hindawi Limited, 2020-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Background. Interleukin-17 plays important roles in allergic diseases. Several studies proved that leptin promoted Th17 immune responses by inducing RORγt transcription. ILC2 is an important member of the early stage of immune response. Therefore, we aimed to explore the effect of leptin on the IL-1...