Molecular mechanisms of post‐burn muscle wasting and the therapeutic potential of physical exercise

• Main Authors: Dorien Dombrecht (Author), Ulrike Van Daele (Author), Birgit Van Asbroeck (Author), David Schieffelers (Author), Pieter‐Jan Guns (Author), Nick Gebruers (Author), Jill Meirte (Author), Eric vanBreda (Author)
• Format: Book
• Published: Wiley, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract After a severe burn injury, a systemic stress response activates metabolic and inflammatory derangements that, among other, leads to muscle mass loss (muscle wasting). These negative effects on skeletal muscle continue for several months or years and are aggravated by short‐term and long‐te...