Matrine suppresses cell growth of diffuse large B-cell lymphoma via inhibiting CaMKIIγ/c-Myc/CDK6 signaling pathway

• Main Authors: Jianyou Gu (Author), Xiao Wang (Author), Ling Zhang (Author), Jingjing Xiang (Author), Jingya Li (Author), Zheng Chen (Author), Yu Zhang (Author), Junfa Chen (Author), Jianping Shen (Author)
• Format: Book
• Published: BMC, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background C-Myc aberrations confer a more aggressive clinic behavior in diffuse large B-cell lymphoma (DLBCL). Matrine is an alkaloid extracted from Sophora flavescens Ait. It possesses anti-cancer property through inhibiting the cell proliferation and inducing the apoptosis. The present s...