Genetic background, recent advances in molecular biology, and development of novel therapy in Alport syndrome

• Main Authors: Kandai Nozu (Author), Yutaka Takaoka (Author), Hirofumi Kai (Author), Minoru Takasato (Author), Kensuke Yabuuchi (Author), Tomohiko Yamamura (Author), Tomoko Horinouchi (Author), Nana Sakakibara (Author), Takeshi Ninchoji (Author), China Nagano (Author), Kazumoto Iijima (Author)
• Format: Book
• Published: The Korean Society of Nephrology, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alport syndrome (AS) is a progressive inherited kidney disease characterized by hearing loss and ocular abnormalities. There are three forms of AS depending on inheritance mode: X-linked Alport syndrome (XLAS), autosomal recessive AS (ARAS), and autosomal dominant AS (ADAS). XLAS is caused by pathog...