Implications of exosomes derived from cholesterol-accumulated astrocytes in Alzheimer's disease pathology

• Main Authors: Qi Wu (Author), Leonardo Cortez (Author), Razieh Kamali-Jamil (Author), Valerie Sim (Author), Holger Wille (Author), Satyabrata Kar (Author)
• Format: Book
• Published: The Company of Biologists, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Amyloid β (Aβ) peptides generated from the amyloid precursor protein (APP) play a critical role in the development of Alzheimer's disease (AD) pathology. Aβ-containing neuronal exosomes, which represent a novel form of intercellular communication, have been shown to influence the function/vulne...