Acute perioperative-stress-induced increase of atherosclerotic plaque volume and vulnerability to rupture in apolipoprotein-E-deficient mice is amenable to statin treatment and IL-6 inhibition

• Main Authors: Henrike Janssen (Author), Christian S. Wagner (Author), Philipp Demmer (Author), Simone Callies (Author), Gesine Sölter (Author), Houra Loghmani-khouzani (Author), Niandan Hu (Author), Harald Schuett (Author), Uwe J. F. Tietge (Author), Gregor Warnecke (Author), Jan Larmann (Author), Gregor Theilmeier (Author)
• Format: Book
• Published: The Company of Biologists, 2015-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Myocardial infarction and stroke are frequent after surgical procedures and consume a considerable amount of benefit of surgical therapy. Perioperative stress, induced by surgery, is composed of hemodynamic and inflammatory reactions. The effects of perioperative stress on atherosclerotic plaques ar...