Cancer-associated fibroblasts mediate resistance to anti-EGFR therapies in cancer

• Main Authors: Shuang Dai (Author), Yingtong Liu (Author), Zheran Liu (Author), Ruidan Li (Author), Feng Luo (Author), Yan Li (Author), Lei Dai (Author), Xingchen Peng (Author)
• Format: Book
• Published: Elsevier, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Over the last decade, epidermal growth factor receptor (EGFR)-targeted therapies have transformed the treatment landscape for patients with advanced solid tumors. Despite these advances, resistance to anti-EGFR therapies is still a significant clinical challenge. While cell-autonomous mechanisms of...